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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
16.67
Human Site:
T373
Identified Species:
22.92
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
T373
V
E
K
G
I
D
L
T
Q
V
K
G
T
G
P
Chimpanzee
Pan troglodytes
XP_522180
647
68973
T373
V
E
K
G
I
D
L
T
Q
V
K
G
T
G
P
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
T373
V
E
K
G
I
D
L
T
Q
V
K
G
T
G
P
Dog
Lupus familis
XP_546524
647
68802
T373
A
E
K
G
I
D
L
T
Q
V
K
G
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
G372
I
D
L
T
Q
V
K
G
T
G
P
E
G
R
I
Rat
Rattus norvegicus
P08461
632
67147
G363
I
D
L
T
Q
V
K
G
T
G
P
E
G
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
D279
R
I
T
K
K
D
I
D
S
F
V
P
S
R
A
Chicken
Gallus gallus
XP_417933
681
72018
K402
A
K
K
L
A
A
E
K
G
I
D
L
A
Q
V
Frog
Xenopus laevis
NP_001082239
628
66845
Q350
E
K
G
I
D
I
K
Q
V
K
G
S
G
P
E
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
V373
K
G
V
D
I
T
Q
V
T
G
T
G
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
D257
H
G
S
I
K
S
G
D
L
A
G
Q
K
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
S252
P
G
G
R
I
L
A
S
D
L
S
Q
A
P
A
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
R232
Q
G
T
G
P
G
G
R
I
V
K
A
D
I
E
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
Y257
V
K
A
D
I
E
D
Y
L
A
S
R
G
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
Y284
V
K
A
D
I
D
E
Y
L
A
S
S
G
K
G
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
A227
S
Q
T
S
G
A
A
A
A
T
P
A
A
A
T
Red Bread Mold
Neurospora crassa
P20285
458
48601
G203
V
K
G
S
G
P
G
G
K
I
T
E
E
D
V
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
6.6
6.6
0
13.3
N.A.
0
N.A.
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
20
20
6.6
13.3
N.A.
0
N.A.
20
20
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
13.3
N.A.
N.A.
20
0
6.6
P-Site Similarity:
26.6
N.A.
N.A.
26.6
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
6
12
12
6
6
18
0
12
18
12
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
18
6
36
6
12
6
0
6
0
6
12
0
% D
% Glu:
6
24
0
0
0
6
12
0
0
0
0
18
6
0
18
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
0
24
18
30
12
6
18
18
6
18
12
30
30
24
12
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
6
0
12
48
6
6
0
6
12
0
0
0
6
12
% I
% Lys:
6
30
30
6
12
0
18
6
6
6
30
0
6
12
0
% K
% Leu:
0
0
12
6
0
6
24
0
18
6
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
0
0
0
6
6
0
0
0
0
18
6
6
12
24
% P
% Gln:
6
6
0
0
12
0
6
6
24
0
0
12
0
6
0
% Q
% Arg:
6
0
0
6
0
0
0
6
0
0
0
6
0
18
0
% R
% Ser:
6
0
6
12
0
6
0
6
6
0
18
12
6
0
0
% S
% Thr:
0
0
18
12
0
6
0
24
18
6
12
0
24
0
6
% T
% Val:
36
0
6
0
0
12
0
6
6
30
6
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _